Neuroscience in the 21st Century: From Basic to Clinical


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Estimated delivery business days. Format Hardcover. Condition Brand New. Description Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience.

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Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year.

Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders.

The World Health Organization estimated in that million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer's and other dementias.

Because neuroscience takes the etiology of disease-the complex interplay between biological, psychological, and sociocultural factors-as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions.

Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. The MOOC reflects our collective vision of what skills and knowledge 21st century neuroscientists should acquire. We are creating an unrivaled course with contributions from remarkable people, leading scientists and innovators across a wide range of disciplines: Biology, neurology, physics, engineering, mathematics, computer science and cognitive science.

This section will cover the basic concepts in neurogenetics; introduce the fields of genomics, transcriptomics, translatomics; classical and cutting-edge experimental approaches; and how integrative simulation can be used to derive biological meaning from genetics data and build bridges from genetics all the way to behaviour.

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This section will cover the basic concepts required to understand the lifecycle of a protein; introduce the fields of translatomics, proteomics, interactomics; classical and cutting-edge experimental approaches; and explore how integrative simulation can be useful to understand the relationship between protein function and brain physiology. This section will cover the structure of the nervous system, from molecules to tissues and their function; experimental approaches to understand cell physiology and cellular interactions; how integrative simulation helps in extracting biological meaning from large amounts of data and establishing causal relationships between cellular morphology, physiology and brain function.

The Future is Now: Medical education for the 21st century

This section will cover the basics of neuronal and glial cell signaling, plasticity, neuromodulation and information storage; experimental approaches; and how integrative simulation is an invaluable tool to model and study synaptic physiology and function in relationship with genomics, proteomics, connectomics and brain function. This section will cover the basics of brain microcircuit architecture from a cellular and structural point of view; network rhythms, function and dysfunction; classical and cutting-edge experimental approaches; and how integrative simulation can bring together knowledge from genetics, cellular neurobiology and synaptic physiology to understand network function in relationship to cognition and behavior.

Neuroscience in the 21st Century | SpringerLink

This section will cover the anatomical organization of the brain and how that supports function; experimental approaches and how integrative simulation can help to elucidate the relationship between anatomy and whole-brain function. The different international initiatives appear complementary, and not duplicative. For example, the US initiative is grounded in experiment: it envisions integrated cellular, anatomical, and physiological data sets of unprecedented scope, rendered intelligible through theoretical and behavioral analyses. These two initiatives will inevitably converge, to the benefit of both.

Neurotechnology and brain-machine interface initiatives have emerged in Japan and Israel, and China and Japan are poised to make unique contributions in primate transgenic models. It is important to emphasize that basic science is international, and knowledge will flow freely between these players; no country will have a monopoly on its contributions. Whether these international efforts would benefit from formal coordination, or be more effectively served by spontaneous collaborations across the international scientific community, are important issues to work out in the coming years.

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Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical
Neuroscience in the 21st Century: From Basic to Clinical Neuroscience in the 21st Century: From Basic to Clinical

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